Cinnamon Molecule With “Insulin-Like Properties” For Type-2 Diabetes

PhytoMedical Technologies, an early stage research based biopharmaceutical company specializing in the discovery, development and eventual commercialization of innovative plant derived pharmaceutical and nutraceutical compounds, today reported that Time Magazine’s December 6th, 2004, cover story (The Year in Medicine from A to Z) referenced the benefits of a molecule found in cinnamon which has “insulin-like properties that may help people with Type-2 diabetes.” A small study of Type-2 diabetes patients who ingested cinnamon had “significantly lower blood levels of glucose, triglycerides and cholesterol after taking cinnamon for 40 days.”

Coincidently, on the same day of the Time Magazine cover story, PhytoMedical announced its intentions to synthesize the active components of several polyphenolic compounds from cinnamon bark that were isolated and characterized over a period of ten years by leading scientists. To review the Company’s December 6th, 2004 press release, please click here: http://www.phytomedical.com/IR/PressReleases/20041206-1.html.

Among other objectives, PhytoMedical plans to synthesize these polyphenolic compounds and characterize their beneficial effects in cell culture systems, animals and ultimately humans. These compounds, which increase insulin sensitivity by activating key enzymes that stimulate insulin receptors while inhibiting the enzymes that deactivate them, have increased sugar metabolism by a factor of 20 in test tube assays using fat cells. Impaired sugar and fat metabolism, present in millions around the world, may lead to Type-2 diabetes and cardiovascular diseases.

Insulin is a hormone made by the pancreas to help the body use glucose (sugar) for energy. In people with Type-2 diabetes, either the pancreas doesn’t make enough insulin or the body is unable to use it correctly. Without sufficient insulin, glucose accumulates in the blood and urine, and the cells of the body are starved, a condition known as diabetes - the leading cause of end-stage renal disease, blindness and lower limb amputations.

Diabetes presently affects over 18.2 million Americans (American Diabetes Association) and is expected to rise to 30 million by 2030 (Centers for Disease Control). As one of the leading causes of death and illness worldwide, diabetes costs the American health care system over $132 billion each year.

“In addition to published studies and a highly successful human study reported in Diabetes Care, a journal of the American Diabetes Association, it’s good to see that a leading and highly reputable magazine has picked up on the benefits of cinnamon and its incredible ability to make insulin more efficient,” comments Mr. Indy Panchi, President and CEO of PhytoMedical Technologies.

Mr. Panchi continues, “Our job now is to develop a naturally derived synthetic end product that can be easily ingested as a pill or added to soft drinks or other liquids, with the end result being lower blood sugar levels through more efficient use of insulin without the risk or side effects of currently available pharmacological treatment options.”

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