Study Findings:
Gleevec (imatinib) has shown promising activity in AIDS-related Kaposi’s sarcoma.
The drug inhibits pathways that spur cancer growth, which led to regression of tumors in five patients within four weeks, the study said. With the other five patients, the disease stabilized and they didn’t develop any new tumors.
“Imatinib is a targeted therapy originally shown to […]
Study Findings:
Cytotoxic T-lymphocytes lifespan was extended upon introduction of the telomerase gene, and demonstrated that bulk cultures of telomerase-transduced CTLs had enhanced HIV suppressing activity that persisted over a longer period of time compared to similar cultures of control cells. The telomerase-transduced CTLs had a prolonged capacity to produce anti-viral cytokines in response to HIV-specific […]
Study Findings:
Anti-HIV drugs inhibited the growth of Plasmodium falciparum, the malaria parasite. These findings may also expose a previously unexplored vulnerability in the parasite that could lead to a new class of anti-malarial drug.
The team tested the effects of the protease inhibitors saquinavir, ritonavir, nelfinavir, amprenavir, and indinavir on a drug-resistant line of P. falciparum. […]