Steroids given to head-trauma patients useless and may be harmful
Study Findings:
- 21% of the patients given steroids had died, compared with 18% of those given the fake drug. The results were the same regardless of how quickly the treatment was administered and regardless of the type or severity of the head injury.
- It remains to be seen whether patients getting steroids fare better in the long term from the disabling effects of the trauma.
Method:
- 10,008 patients in 49 countries who had severe head injuries were randomly allocated either a steroid drip or a fake drip for 48 hours after being admitted to the emergency room.
Related Articles:
- Steroids not helpful for head injury, study shows
- Original research: Effect of intravenous corticosteroids on death within 14 days in 10 008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial
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